Vonoprazan Fumarate Impurity 83 CAS 928325-41-1 (free base)
| CAS No. | 928325-41-1 (free base) |
| Molecular Formula | C17H15F2N3O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Vonoprazan Fumarate Impurity 83 (C17H15F2N3O2SC4H4O4) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Vonoprazan Fumarate Impurity 83 (CAS 928325-41-1 (free base)), a pharmacopoeial impurity reference standard (molecular formula C17H15F2N3O2SC4H4O4, MW 479.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H15F2N3O2S C4H4O4 |
| Molecular Weight | 479.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Impurity 298 (CAS 103860-56-6)
- Vonoprazan Impurity 82 (CAS 106058-86-0)
- Vonoprazan Fumarate Impurity 71 (CAS 1060802-18-7)
- Vonoprazan Impurity 129 (CAS 109-00-2)
- Vonoprazan Impurity 188 (CAS 111480-82-1)
- Vonoprazan Impurity 195 (CAS 1126403-28-8)
- Vonoprazan Impurity 10 (CAS 122453-85-4)
- Vonoprazan Impurity 89 (CAS 1224739-02-9)
Recommended Standards
- Finerenone Impurity 138 (CAS CATO-C4X-2880138)
- Nicotinamide impurity 19 (CAS CATO-C4X-200019)
- Valdecoxib Impurity 1 (CAS CATO-C4X-14511)
- Methyl 5-bromo-2-hydroxy-3-methoxybenzoate (CAS 134419-43-5)
- 3-(2-Fluorophenoxy)piperidine hydrochloride (CAS 1185299-30-2)
- 5-{[4-(propan-2-yl)phenyl]amino}-1,3,4-thiadiazole-2-thiol (CAS 380335-66-0)
- 6-Phenyl-2-azaspiro[3.3]Heptane (CAS 1774896-02-4)
- Thiazol-5-ylmethanamine (CAS 161805-76-1)
- tert-Butyl 14-oxo-6,10,13-triazadispiro[4.1.5.2]tetradecane-10-carboxylate (CAS 946384-61-8)
- Peptide 439 (CAS CATO-CPTD788439)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com